SELECTED PUBLICATIONS

• Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape. Lorent JH, Levental KR, Ganesan L, Rivera-Longsworth G, Sezgin E, Doktorova MD, Lyman E, Levental I. Nat Chem Biol 2020.
• Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness. Levental KR, Malmberg E, Symons JL, Fan YY, Chapkin RS, Ernst R, Levental I. Nature Communications 2020.
• Direct label-free imaging of nanodomains in biomimetic and biological membranes by cryogenic electron microscopy.
  Heberle FA, Doktorova M, Scott HL, Skinkle AD, Waxham MN, Levental I. Proc Natl Acad Sci U S A. 2020. **Cover article
• ω-3 polyunsaturated fatty acids direct differentiation of the membrane phenotype in mesenchymal stem cells to potentiate osteogenesis.  Levental KR, Surma MA, Skinkle AD, Lorent JH, Zhou Y, Klose C, Chang JT, Hancock JF, Levental I. Science Advances 2017
• ​Structural determinants and functional consequences of protein affinity for membrane rafts. Lorent JH, Diaz-Rohrer B, Lin X, Spring K, Gorfe AA, Levental KR, Levental I.  Nature Communications 2017
• ​Membrane raft association is a determinant of plasma membrane localization.  Diaz-Rohrer B*, Levental KR*, Simons K, Levental I.  Proceedings National Academy of Science USA. 2014  (PDF)  **Cover Article
• The mystery of membrane organization: composition, regulation and roles of lipid rafts. Sezgin E, Levental I, Mayor S, Eggeling C. Nature Reviews Molecular Cell Biology 2017.
• ​​Elucidating membrane structure and protein behavior using Giant Plasma Membrane Vesicles. Sezgin E, Kaiser HJ, Baumgart T, Schwille P, Simons K, Levental I. Nature Protocols 2012. May 3;7(6):1042-51.  (PDF)  **Cover Article

2023

• Coupling of protein condensates to ordered lipid domains determines functional membrane organization.
  Wang HY, Chan SH, Dey S, Castello-Serrano I, Rosen MK, Ditlev JA, Levental KR, Levental I. Science Advances 2023.
• Rab3 mediates a pathway for endocytic sorting and plasma membrane recycling of ordered microdomains​. Diaz-Rohrer B, Castello-Serrano I, Chan SZ, Wang H-Y, Shurer CR, Levental KR, Levental I. Proceedings National Academy of Science USA 2023.
• Lipid packing is disrupted in copolymeric nanodiscs compared with intact membranes. Real Hernandez LM, Levental I. Biophys J 2023.
• Membrane phase separation drives responsive assembly of receptor signaling domains. Shelby SA, Castello-Serrano I, Wisser KC, Levental I, Veatch SL. Nature Chemical Biology 2023.
• Archaeal DNA-import apparatus is homologous to bacterial conjugation machinery. Beltran LC, Cvirkaite-Krupovic V, Miller J, Wang F, Kreutzberger MAB, Patkowski JB, Costa TRD, Schouten S, Levental I, Conticello VP, Egelman EH, Krupovic M. Nature Communications 2023.
• Serinc5 Restricts HIV Membrane Fusion by Altering Lipid Order and Heterogeneity in the Viral Membrane.
  Ward AE, Sokovikova D, Waxham MN, Heberle FA, Levental I, Levental KR, Kiessling V, White JM, Tamm LK. ACS Infectious Diseases 2023.
• Membranes in focus. Sezgin E, Levental I. Biophysical Journal 2023.
• Seeing the Membrane from Both Sides Now: Lipid Asymmetry and Its Strange Consequences. Doktorova M, Levental I, Heberle FA. Cold Spring Harb Perspect Biol 2023.
  
• Unsaturated Lipids Facilitate Partitioning of Transmembrane Peptides into the Liquid Ordered Phase. Park S, Levental I, Pastor RW, Im W. J Chem Theory Comput 2023.
  

2022

• Regulation of membrane protein structure and function by their lipid nano-environment. Levental I, Lyman E.  Nat Rev Mol Cell Biol 2022.
  
• Lipid-Protein Interactions in Plasma Membrane Organization and Function.  Sych T, Levental KR, Sezgin E.  Annu Rev Biophys 2022.
• Cholesterol's balancing act: Defying the status quo. Doktorova M, Levental I.  Biophys J 2022.
  

2021

•  SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation. Sanders DW, Jumper CC, Ackerman PJ, Bracha D, Donlic A, Kim H, Kenney D, Castello-Serrano I, Suzuki S, Tamura T, Tavares AH, Saeed M, Holehouse AS, Ploss A, Levental I, Douam F, Padera RF, Levy BD, Brangwynne CP. Elife 2021.
• Reply to JJ Christensen et al. Zinöcker MK, Svendsen K, Levental KR, Levental I, Dankel SN.  Am J Clin Nutr 2021. 
  
• Proteomic and lipidomic profiling of demyelinating lesions identifies fatty acids as modulators in lesion recovery.
  Penkert H, Bertrand A, Tiwari V, Breimann S, Müller SA, Jordan PM, Gerl MJ, Klose C, Cantuti-Castelvetri L, Bosch-Queralt M, Levental I, Lichtenthaler SF, Werz O, Simons M.  Cell Rep 2021.
  
• Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis.  Matias MI, Yong CS, Foroushani A, Goldsmith C, Mongellaz C, Sezgin E, Levental KR, Talebi A, Perrault J, Rivière A, Dehairs J, Delos O, Bertand-Michel J, Portais JC, Wong M, Marie JC, Kelekar A, Kinet S, Zimmermann VS, Levental I, Yvan-Charvet L, Swinnen JV, Muljo SA, Hernandez-Vargas H, Tardito S, Taylor N, Dardalhon V.  Cell Rep 2021.
  

2020

• Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness.  Levental KR, Malmberg E, Symons JL, Fan YY, Chapkin RS, Ernst R, Levental I. Nat Commun 2020. 
• Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape. Lorent JH, Levental KR, Ganesan L, Rivera-Longsworth G, Sezgin E, Doktorova MD, Lyman E, Levental I. Nat Chem Biol 2020.
• Lipid Rafts: Controversies Resolved, Mysteries Remain. Levental I, Levental KR, Heberle FA. Trends Cell Biol 2020.
• Structural and functional consequences of reversible lipid asymmetry in living membranes. Doktorova M, Symons JL, Levental I. Nat Chem Biol. 2020.
• Direct label-free imaging of nanodomains in biomimetic and biological membranes by cryogenic electron microscopy.
  Heberle FA, Doktorova M, Scott HL, Skinkle AD, Waxham MN, Levental I. Proc Natl Acad Sci U S A. 2020. **Cover article
• Lipidomic atlas of mammalian cell membranes reveals hierarchical variation induced by culture 2 conditions, subcellular membranes, and cell lineages. Symons JL, Cho K, Chang JT, Du G, Waxham MN, Hancock JF, Levental I,  and Levental KR, Soft Matter 2020.
• Myelin-Associated MAL and PLP Are Unusual Among Multi-Pass Transmembrane Proteins in Preferring Ordered Membrane Domains. Castello-Serrano I, Lorent JH, Ippolito R, Levental KR, Levental I.  J Phys Chem B. 2020.  **Cover article
• Lipid rafts come of age. Levental I. Nat Rev Mol Cell Biol 2020.
• Membrane Heterogeneity Beyond the Plasma Membrane. Wang HY, Bharti D, Levental I. Front Cell Dev Biol. 2020
• Computational and Experimental Advances in Biomembranes: Resolving Their Complexity. Marrink SJ, Levental I. J Phys Chem B. 2020
• Composition dependence of cholesterol flip-flop rates in physiological mixtures. Baral S, Levental I, Lyman E. Chem Phys Lipids. 2020
• Cell-Derived Plasma Membrane Vesicles Are Permeable to Hydrophilic Macromolecules. Skinkle AD, Levental KR, Levental I. Biophysical Journal 2020. 
• Membrane domains beyond the reach of microscopy. Levental I, Wang H. J Lipid Res. 2020.
• Regulation of lipid saturation without sensing membrane fluidity. Ballweg S, Sezgin E, Doktorova M, Covino R, Reinhard J, Wunnicke D, Hänelt I, Levental I, Hummer G, Ernst R. Nat Commun 2020.
• ​Creating Supported Plasma Membrane Bilayers Using Acoustic Pressure. Sezgin E, Carugo D, Levental I, Stride E, Eggeling C. Membranes 2020. 
• Maturation of Monocyte-Derived DCs Leads to Increased Cellular Stiffness, Higher Membrane Fluidity, and Changed Lipid Composition.
  Lühr JJ, Alex N, Amon L, Kräter M, Kubánková M, Sezgin E, Lehmann CHK, Heger L, Heidkamp GF, Smith AS, Zaburdaev V, Böckmann RA, Levental I, Dustin ML, Eggeling C, Guck J, Dudziak D. Front Immunol. 2020

2019

• On the Mechanism of Bilayer Separation by Extrusion, or Why Your LUVs Are Not Really Unilamellar. Scott HL, Skinkle A, Kelley EG, Waxham MN, Levental I, Heberle FA. Biophys J 2019.
• Reduced level of docosahexaenoic acid shifts GPCR neuroreceptors to less ordered membrane regions. Javanainen M, Enkavi G, Guixà-Gonzaléz R, Kulig W, Martinez-Seara H, Levental I, Vattulainen I. PLoS Comput Biol 2019.
• The desmosome is a mesoscale lipid raft-like membrane domain. Lewis JD, Caldara AL, Zimmer SE, Stahley SN, Seybold A, Strong NL, Frangakis AS, Levental I, Wahl JK, Mattheyses AL, Sasaki T, Nakabayashi K, Hata K, Matsubara Y, Ishida-Yamamoto A, Amagai M, Kubo A, Kowalczyk AP. Mol Biol Cell 2019.
• HRAS-driven cancer cells are vulnerable to TRPML1 inhibition. Jung J, Cho KJ, Naji AK, Clemons KN, Wong CO, Villanueva M, Gregory S, Karagas NE, Tan L, Liang H, Rousseau MA, Tomasevich KM, Sikora AG, Levental I, van der Hoeven D, Zhou Y, Hancock JF, Venkatachalam K. EMBO Rep 2019.
• Membrane cholesterol depletion reduces downstream signaling activity of the adenosine A2Areceptor. McGraw C, Yang L, Levental I, Lyman E, Robinson AS. Biochim Biophys Acta Biomembr 2019.
• Eicosapentaenoic acid in combination with EPHA2 inhibition shows efficacy in preclinical models of triple-negative breast cancer by disrupting cellular cholesterol efflux. Torres-Adorno AM, Vitrac H, Qi Y, Tan L, Levental KR, Fan YY, Yang P, Chapkin RS, Eckhardt BL, Ueno NT. Oncogene 2019.
• Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine. Madison MC, Landers CT, Gu BH, Chang CY, Tung HY, You R, Hong MJ, Baghaei N, Song LZ, Porter P, Putluri N, Salas R, Gilbert BE, Levental I, Campen MJ, Corry DB, Kheradmand F. J Clin Invest 2019.

2018

• Protein Partitioning into Ordered Membrane Domains: Insights from Simulations. Lin X, Gorfe AA, Levental I. Biophys J. 2018
• Cellular mechanisms of physicochemical membrane homeostasis. Ernst R, Ballweg S, Levental I. Curr Opin Cell Biol. 2018
• Plasma Gelsolin: Indicator of Inflammation and Its Potential as a Diagnostic Tool and Therapeutic Target. Piktel E, Levental I, Durnaś B, Janmey PA, Bucki R. Int J Mol Sci. 2018 ​
• ​Tuning Length Scales of Small Domains in Cell-Derived Membranes and Synthetic Model Membranes. Cornell CE, Skinkle AD, He S, Levental I, Levental KR, Keller SL. Biophys J. 2018
  

2017

• ω-3 polyunsaturated fatty acids direct differentiation of the membrane phenotype in mesenchymal stem cells to potentiate osteogenesis.  Levental KR, Surma MA, Skinkle AD, Lorent JH, Zhou Y, Klose C, Chang JT, Hancock JF, Levental I. Science Advances 2017.
• ​Structural determinants and functional consequences of protein affinity for membrane rafts. Lorent JH, Diaz-Rohrer B, Lin X, Spring K, Gorfe AA, Levental KR, Levental I.  Nature Communications 2017.
• n-Alcohol length governs shift in Lo-Ld mixing temperatures in synthetic and cell-derived membranes. Cornell CE, McCarthy NLC, Levental KR, Levental I, Brooks NJ, Keller SL. Biophys J 2017.
• ​Miscibility Transition Temperature Scales with Growth Temperature in a Zebrafish Cell Line. Burns M, Wisser K, Wu J, Levental I, Veatch SL. Biophys J 2017.
• ​The mystery of membrane organization: composition, regulation and roles of lipid rafts. Sezgin E, Levental I, Mayor S, Eggeling C. Nat Rev Mol Cell Biol 2017.
• ​Click chemistry based high throughput screening platform for modulators of Ras palmitoylation.  Ganesan L, Shieh P, Bertozzi CR, Levental I. Scientific Reports 2017.
  
• ​Sphingomyelin metabolism is a regulator of KRAS function. van der Hoeven D, Cho KJ, Zhou Y, Ma X, Chen W, Naji A, Montufar-Solis D, Zuo Y, Kovar SE, Levental KR, Frost JA, van der Hoeven R, Hancock JF. Mol Cell Biol. 2017
• ​Phase Partitioning of GM1 and Its Bodipy-Labeled Analog Determine Their Different Binding to Cholera Toxin. Rissanen S, Grzybek M, Orłowski A, Róg T, Cramariuc O, Levental I, Eggeling C, Sezgin E, Vattulainen I. Front Physiol 2017.
• ​Lipin-1 regulation of phospholipid synthesis maintains endoplasmic reticulum homeostasis and is critical for triple-negative breast cancer cell survival. He J, Zhang F, Tay LW, Boroda S, Nian W, Levental KR, Levental I, Harris TE, Chang JT, Du G. FASEB J 2017.

2016

• Domain stability in biomimetic membranes driven by lipid polyunsaturation. Lin X, Lorent JH, Skinkle AD, Levental KR, Waxham MN, Gorfe AA, Levental I. J Phys Chem B 2016.
• Modular GAG-matrices to promote mammary epithelial morphogenesis in vitro. Nowak M, Freudenberg U, Tsurkan MV, Werner C, Levental KR. Biomaterials 2016.
• The aliphatic chain of cholesterol modulates bilayer interleaflet coupling and domain registration. Lin X, Zhang S, Ding H, Levental I, Gorfe AA. FEBS Letters 2016. (PDF)
• The Continuing Mystery of Lipid Rafts. Levental I and Veatch SL. J Mol Biol 2016. (PDF)
• Remodeling of the postsynaptic plasma membrane during neural development. Tulodziecka K, Diaz-Rohrer BB, Farley MM, Chan RB, Di Paolo G, Levental KR, Waxham MN, Levental I. Mol Biol Cell 2016. (PDF)
• Polyunsaturated lipids regulate membrane domain stability by tuning membrane order. Levental KR, Lorent JH, Lin X, Skinkle AD, Surma MA, Stockenbojer EA, Gorfe AA, Levental I.  Biophys J 2016.   (PDF)
• Motility and stem cell properties induced by the epithelial-mesenchymal transition require destabilization of lipid rafts.  Tisza MJ, Zhao W, Fuentes JSR, Prijic S, Chen X, Levental I, Chang JT.  Oncotarget 2016.  (PDF)

2015

• Pharmacological Inhibition of Protein Lipidation.  Ganesan L, Levental I.  J Membr Biol.  2015   (PDF)
  
• Structural determinants of protein partitioning into ordered membrane domains and lipid rafts.  Lorent JH, Levental I.  Chem Phys Lipids.  2015  (PDF)
  
• Giant plasma membrane vesicles: models for understanding membrane organization.  Levental KR and Levental I.  Curr Top Membr. 2015 
  
• Adaptive lipid packing and bioactivity in membrane domains.  Sezgin E, Gutmann T, Buhl T, Dirkx R, Grzybek M, Coskun Ü, Solimena M, Simons K, Levental I, Schwille P.  PLoS One.  2015  (PDF)
  
• Isolation of Giant Plasma Membrane Vesicles for Evaluation of Plasma Membrane Structure and Protein Partitioning. Levental KR and Levental I. Methods Mol Biol. 2015  (PDF)
  
• Nanoclusters of the resting T cell antigen receptor (TCR) localize to non-raft domains.  Beck-Garcia K, Beck-Garcia E, Bohler S, Zorzin C, Sezgin E, Levental I, Alarcon B, Schamel WW. Biochim Biophys Acta.  2015    (PDF)
  
• Simvastatin prevents triple-negative breast cancer metastasis in pre-clinical models through regulation of FOXO3a.​  Wolfe AR, Debeb BG, Lacerda L, Larson R, Bambhroliya A, Huang X, Bertucci F, Finetti P, Birnbaum D, Van Laere S, Diagaradjan P, Ruffell B, Trenton NJ, Chu K, Hittelman W, Diehl M, Levental I, Ueno NT, Woodward WA.  Breast Cancer Res Treat.  2015  
  
• Heparin desulfation modulates VEGF release and angiogenesis in diabetic wounds.  Freudenberg U, Zieris A, Chwalek K, Tsurkan MV, Maitz MF, Atallah P, Levental KR, Eming SA, Werner C.  J Control Release.  2015  (PDF)
  
• The Role of Cathelicidin LL-37 in Cancer Development.  Piktel E, Niemirowicz K, Wnorowska U, Wątek M, Wollny T, Głuszek K, Góźdź S, Levental I, Bucki R.  Arch Immunol Ther Exp.  2015
  
• Role played by Prx1-dependent extracellular matrix properties in vascular smooth muscle development in embryonic lungs.  Ihida-Stansbury K, Ames J, Chokshi M, Aiad N, Sanyal S, Kawabata KC, Levental I, Sundararaghavan HG, Burdick JA, Janmey P, Miyazono K, Wells RG, Jones PL. Pulm Circ.  2015

2014

• Membrane raft association is a determinant of plasma membrane localization.  Diaz-Rohrer B*, Levental KR*, Simons K, Levental I.  Proc Natl Acad Sci USA. 2014  (PDF)  **Cover Article
• Rafting through traffic: Membrane domains in cellular logistics. Diaz-Roher B, Levental KR, Levental I. Biochim Biophys Acta. 2014 (PDF)
• Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression.  Mouw JK, Yui Y, Damiano L, Bainer RO, Lakins JN, Acerbi I, Ou G, Wijekoon AC, Levental KR, Gilbert PM, Hwang ES, Chen YY, Weaver VM.  Nat Med.  2014 Apr;20(4):360-7. (PDF)a
• The cholesterol-binding motif of the HIV-1 glycoprotein gp41 regulates lateral sorting and oligomerization.  Schwarzer R, Levental I, Gramatica A, Scolari S, Buschmann V, Veit M, Herrmann A. Cell Microbiol.  2014 (PDF) 

2013

• Bile acids modulate signaling through functional perturbation of plasma membrane domains.  Zhou Y, Maxwell KN, Sezgin E, Lu M, Liang H, Hancock JF, Dial EJ, Lichtenberger LM, Levental I.  J Biol Chem. 2013 (PDF)  **Cover Article
• Photoconversion of bodipy-labeled lipid analogues.  Sezgin E, Chwastek G, Aydogan G, Levental I, Simons K, Schwille P. Chembiochem 2013. Apr 15;14(6):695-698.  (PDF)  **Cover Article
• Defined polymer-peptide conjugates to form cell-instructive starPEG-heparin matrices in situ.  Tsurkan MV, Chwalek K, Prokoph S, Zieris A, Levental KR, Freudenberg U, Werner C.  Advanced Materials 2013.  May 14;25(18):2606-10.  (PDF)

2012

• Elucidating membrane structure and protein behavior using Giant Plasma Membrane Vesicles. Sezgin E, Kaiser HJ, Baumgart T, Schwille P, Simons K, Levental I. Nature Protocols 2012. May 3;7(6):1042-51.  (PDF)  **Cover Article 
• Partitioning, diffusion, and ligand binding of raft lipid analogs in model and cellular plasma membranes.  Sezgin E, Levental I, Grzybek M, Schwarzmann G, Mueller V, Honigmann A, Belov VN, Eggeling C, Coskun U, Simons K, Schwille P.  Biochim Biophys Acta 2012. Mar 17;1818(7):1777-1784. (PDF)
• Sustained delivery of SDF-1a from heparin-based hydrogels to attract circulating pro-angiogenic cells.  Prokoph S, Chavakis E, Levental KR, Zieris A, Freudenberg U, Dimmeler S, Werner C.  Biomaterials. 2012 June; 33(19):4792-800.  (PDF)

2011

• Molecular convergence of bacterial and eukaryotic surface order. Kaiser HJ, Surma MA, Mayer F, Levental I, Grzybek M, Klemm RW, Da Cruz S, Meisinger C, Müller V, Simons K, Lingwood D. J Biol Chem. 2011 Nov 25;286(47):40631-7. (PDF)
• Raft domains of variable properties and compositions in plasma membrane vesicles. Levental I, Grzybek M, Simons K. Proc Natl Acad Sci USA. 2011 Jul 12;108(28):11411-6. (PDF)
• Intrinsic membrane association of the cytoplasmic tail of influenza virus M2 protein and lateral membrane sorting regulated by cholesterol binding and palmitoylation. Thaa B, Levental I, Herrmann A, Veit M. Biochem J. 2011 Aug 1;437(3):389-97. (PDF)
• Two-tier hydrogel degradation to boost endothelial cell morphogenesis.  Chwalek K, Levental KR, Tsurkan MV, Zieris A, Freudenberg U, Werner C.  Biomaterials. 2011 Dec;32(36):9649-57. (PDF)
• Dual independent delivery of pro-angiogenic growth factors from starPEG-heparin hydrogels. Zieris A, Chwalek K, Prokoph S, Levental KR, Welzel PB, Freudenberg U, Werner C.  J Control Release. 2011 Nov 30;156(1):28-36. (PDF)

2010

• A simple indentation device for measuring micrometer-scale tissue stiffness. Levental I, Levental KR, Klein EA, Assoian R, Miller RT, Wells RG, Janmey PA. J Phys Condens Matter. 2010 May 19;22(19):194120. (PDF)
• Palmitoylation regulates raft affinity for the majority of integral raft proteins. Levental I, Lingwood D, Grzybek M, Coskun U, Simons K. Proc Natl Acad Sci USA. 2010 Dec 21;107(51):22050-4.  (PDF)  **Recommended in Faculty of 1000: Current rating = 6
• Greasing their way: lipid modifications determine protein association with membrane rafts. Levental I, Grzybek M, Simons K. Biochemistry. 2010 Aug 3;49(30):6305-16. (PDF)  **4th most downloaded article in Biochemistry for 2010 
• Modular starPEG-heparin gels with bifunctional peptide linkers. Tsurkan MV, Chwalek K, Levental KR, Freudenberg U, Werner C.  Macromol Rapid Commun. 2010 Sep 1;31(17):1529-33. (PDF)
• FGF-2 and VEGF functionalization of starPEG-heparin hydrogels to modulate biomolecular and physical cues of angiogenesis. Zieris A, Prokoph S, Levental KR, Welzel PB, Grimmer M, Freudenberg U, Werner C. Biomaterials. 2010 Nov;31(13):7985-94.  (PDF)
• Enzymatically degradable heparin-polyethylene glycol gels with controlled mechanical properties.  Tsurkan MV, Levental KR, Freudenberg U, Werner C.  Chem Commun. 2010 Feb 21;46(7):1141-3.  
• Analytical approaches to uptake and release of hydrogel-associated FGF-2. Zieris A, Prokoph S, Welzel PB, Grimmer M, Levental KR, Panyanuwat W, Freudenberg U, Werner C. J Mater Sci: Mater Med. 2010 Mar;21(3):915-23.  (PDF)

2009

• Cholesterol-dependent phase separation in cell-derived giant plasma-membrane vesicles. Levental I, Byfield FJ, Chowdhury P, Gai F, Baumgart T, Janmey PA. Biochem J. 2009 Nov 11;424(2):163-7. (PDF)  **Highlighted in Biochem J
• Order of lipid phases in model and plasma membranes. Kaiser HJ, Lingwood D, Levental I, Sampaio JL, Kalvodova L, Rajendran L, Simons K. Proc Natl Acad Sci USA. 2009 Sep 29;106(39):16645-50. (PDF)
• Cell-cycle control by physiological matrix elasticity and in vivo tissue stiffening. Klein EA, Yin L, Kothapalli D, Castagnino P, Byfield FJ, Xu T, Levental I, Hawthorne E, Janmey PA, Assoian RK. Curr Biol. 2009 Sep 29;19(18):1511-8. (PDF)
• Lipid rafts as functional heterogeneity in cell membranes. Lingwood D, Kaiser HJ, Levental I, Simons K. Biochem Soc Trans. 2009 Oct;37(Pt 5):955-60. (PDF)
• Spotted vesicles, striped micelles and Janus assemblies induced by ligand binding. Christian DA, Tian A, Ellenbroek WG, Levental I, Rajagopal K, Janmey PA, Liu AJ, Baumgart T, Discher DE. Nat Mater. 2009 Oct;8(10):843-9. (PDF) 
• Calcium-dependent lateral organization in phosphatidylinositol 4,5-bisphosphate (PIP2)- and cholesterol-containing monolayers. Levental I, Christian DA, Wang YH, Madara JJ, Discher DE, Janmey PA. Biochemistry. 2009 Sep 1;48(34):8241-8. (PDF)
• Absence of filamin A prevents cells from responding to stiffness gradients on gels coated with collagen but not fibronectin. Byfield FJ, Wen Q, Levental I, Nordstrom K, Arratia PE, Miller RT, Janmey PA. Biophys J. 2009 Jun 17;96(12):5095-102. (PDF)
• Mechanically induced reactive gliosis causes ATP-mediated alterations in astrocyte stiffness. Miller WJ, Levental I, Scarsella D, Haydon PG, Janmey P, Meaney DF. J Neurotrauma. 2009 May;26(5):789-97.  (PDF)
• Matrix crosslinking forces tumor progression by enhancing integrin signaling. Levental KR, Yu H, Kass L, Lakins JN, Egeblad M, Erler JT, Fong SF, Csiszar K, Giaccia A, Weninger W, Yamauchi M, Gasser DL, Weaver VM. Cell. 2009 Nov 25;139(5):891-906.  (PDF)  ** Highlighted in Cancer Cell and Nature.

2008

• Plasma gelsolin: function, prognostic value, and potential therapeutic use. Bucki R, Levental I, Kulakowska A, Janmey PA. Curr Protein Pept Sci. 2008 Dec;9(6):541-51. (PDF)
• Critical exponents for line tension and dipole density difference from lipid monolayer domain boundary fluctuations. Heinrich MC, Levental I, Gelman H, Janmey PA, Baumgart T. J Phys Chem B. 2008 Jul 10;112(27):8063-8.  (PDF)
• Combined electrostatics and hydrogen bonding determine intermolecular interactions between polyphosphoinositides. Levental I, Cēbers A, Janmey PA. J Am Chem Soc. 2008 Jul 16;130(28):9025-30. (PDF)
• Electrostatic contribution to the surface pressure of charged monolayers containing polyphosphoinositides. Levental I, Janmey PA, Cēbers A. Biophys J. 2008 Aug;95(3):1199-205.  (PDF)

2007

• Fibroblast adaptation and stiffness matching to soft elastic substrates. Solon J, Levental I, Sengupta K, Georges PC, Janmey PA. Biophys J. 2007 Dec 15;93(12):4453-61. (PDF)
• HIV infection changes glomerular podocyte cytoskeletal composition and results in distinct cellular mechanical properties. Tandon R, Levental I, Huang C, Byfield FJ, Ziembicki J, Schelling JR, Bruggeman LA, Sedor JR, Janmey PA, Miller RT. Am J Physiol Renal Physiol. 2007 Feb;292(2):F701-10. (PDF)
• Antibacterial Peptides - A Bright Future or a False Hope. Bucki R, Levental I, Janmey PA. Anti-Infective Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Anti-Infective Agents). 2007 Jul;6(3)175-184. (PDF)
• Soft biological materials and their impact on cell function.  Levental I, Georges PC, Janmey PA. Soft Matter. 2007 (3):299-306.  (PDF)
• Demystifying the effects of three-dimensional microenvironment in tissue morphogenesis.  Johnson KR, Leight JL, Weaver VM.  Methods Cell Biol. 2007; 83:547-83.  (PDF)

2005

Tensional homeostasis and the malignant phenotype.  Paszek MJ, Zahir N, Johnson KR, Lakins JN, Rozenberg GI, Gefen A, Reinhart-King CA, Margulies SS, Dembo M, Boettiger D, Hammer DA, Weaver VM.  Cancer Cell. 2005 Sep;8(3):241-54.  (PDF)